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Sunday brings the inaugural Wear-Tyne derby after 2024, but who will emerge victorious – Sunderland or Newcastle?
"For most of last season, no one would have predicted the Wearside club rising to the top flight and holding their own with Eddie Howe's Newcastle, let alone being above them in the table," remarked analyst Chris Sutton.
"The situation is very different now, and the way Sunderland play leads me to believe they've got a real chance."
The analyst is providing predictions for all 380 Premier League games this campaign, against AI, the public and a variety of guests.
For week 16, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the national gaming squad – the Football Association's formal esports team – at the football simulation Uefa eEuro 2025 finals tournament, which will occur at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, Instagram Live and short-form video channels, as well as EA Sports FC Twitch and YouTube and the national team's Twitch.
Are you in alignment with their predictions? Feel free to submit your own projections below.
The most popular scoreline picked for each game is used in the leaderboards at the end of this page.
A correct result (choosing a win, draw or defeat) is worth 10 points. A perfect prediction earns 40 points.
Ray, who represents his club side and the Premier League champions as well as England, is competing for the first time at the eEuros finals after successfully navigating the qualification rounds.
Eight players will fly the flag at the finals in a knockout format, playing for a six-figure prize fund and a highly sought-after spot in the global championship qualifiers, with Denmark's Anders Vejrgang defending the title he won last year.
"I'm feeling really good for it," Ray stated. "I've got a really good coach alongside me and preparation has been going well.
"It's always an honour to play for your country. Naturally when you are younger, you imagine doing it as an real-life footballer, but when you go into this profession and there is an chance to represent England, wearing the Three Lions is something unique.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"In my opinion he is the top competitor in the world so defeating him in a tournament like this just provides a huge surge of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were excellent against the Gunners at the end of November, when they earned a stalemate after going down to 10 men, and I was thinking they've turned a corner, they could possibly be title contenders.
In the matches following, however, they were outfought by Leeds, looked lethargic against Bournemouth and this week got turned over by Atalanta in the Champions League.
So boss Enzo Maresca really needs a win here to return to winning ways, but it is a tough ask because Everton are such a threatening team.
Their key midfielders are playing really well and Everton have got a bit of form at the moment.
Based on recent performances you would likely back the visitors, while the most logical prediction would likely be a draw, but I'm throwing caution to the wind.
The Blues have failed to given me any good cause to back them recently, but I just have a hunch they will win this match because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be fascinating to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot ought not to put up with that distraction. I know Salah has been a legend for Liverpool but fundamentally Slot just wants to win games and there is no ulterior motive in his team selection.
They changed their tactical setup against Inter and went with a midfield diamond formation and two up top.
The media is going to be talking about whether Salah is included for this game, but the only way he is going to be brought back into the fold is if he says sorry.
Slot's attention will be on winning this game, but it is a difficult fixture.
One might suggest it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to a consistent run of form, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will probably lose now - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the benefit of a free week while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Aside from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, particularly straight after they've played in the Champions League.
It is anticipated that that pattern to continue on Sunday, and their tiredness is likely to be a factor in how this game goes because of their rivals' high press.
We saw how incessant Regis le Bris's side are. They bullied the Gunners, and it was a joy to watch.
Commentators talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been superb, but Noah Sadiki, who plays alongside him, has also been one of the best acquisitions and deserves some attention too.
All signs point to this being the best game|most exciting fixture